Modelones
Modelones Builder Gel Clear
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Check Price on AmazonEditorial review: BuilderGel.app team · Updated · Ingredient-source review, not medical advice
Also known as: Trimethylbenzoyl Diphenylphosphine Oxide, 2,4,6-Trimethylbenzoyl-diphenylphosphine oxide
TPO (Trimethylbenzoyl Diphenylphosphine Oxide) is a photoinitiator used in UV/LED curable gel nail products to initiate polymerization upon light exposure. It has been classified as a potential skin sensitizer, and there are concerns about endocrine-disrupting properties. The EU has tightened restrictions on its use in cosmetics. Incomplete curing (under-curing a gel layer) can leave residual unreacted TPO, significantly increasing dermal exposure risk.
Common product types
Regulatory status
European Commission guidance says TPO-containing cosmetic products are prohibited on the EU market from September 1, 2025 after CMR category 1B classification and inclusion in Annex II of the Cosmetics Regulation.
These products are marked HEMA-free in our database and do not disclose TPO. They are lower-risk starting points, not allergy-proof choices.
Modelones
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As an Amazon Associate, BuilderGel.app earns from qualifying purchases. This purchase link does not affect the disclosure finding.
Check Price on AmazonModelones
Marketplace & purchase
As an Amazon Associate, BuilderGel.app earns from qualifying purchases. This purchase link does not affect the disclosure finding.
Check Price on AmazonModelones
Marketplace & purchase
As an Amazon Associate, BuilderGel.app earns from qualifying purchases. This purchase link does not affect the disclosure finding.
Check Price on AmazonBeetles
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As an Amazon Associate, BuilderGel.app earns from qualifying purchases. This purchase link does not affect the disclosure finding.
Check Price on AmazonTPO (Trimethylbenzoyl Diphenylphosphine Oxide) is a photoinitiator used in UV/LED curable gel nail products to initiate polymerization upon light exposure. It has been classified as a potential skin sensitizer, and there are concerns about endocrine-disrupting properties. The EU has tightened restrictions on its use in cosmetics. Incomplete curing (under-curing a gel layer) can leave residual unreacted TPO, significantly increasing dermal exposure risk.
TPO is classified as medium risk in our system. Photoinitiator used in UV/LED gel systems. Potential sensitizer and endocrine disruptor concern.
TPO may also appear as: Trimethylbenzoyl Diphenylphosphine Oxide, 2,4,6-Trimethylbenzoyl-diphenylphosphine oxide.
This page is educational and does not diagnose allergy. Ingredient labels and formulas can change; verify the current package and ask a healthcare professional if you have symptoms or a known acrylate allergy.